Cell Invasion Assay (3D)
Orisâ¢ : A SIMPLE PLATFORM FOR PUBLICATION-READY DATA
In the Orisâ¢ 3D Cell Invasion Assay, stoppers are used to create a central collagen-containing Detection Zone for cell invasion experiments.
Cells are suspended in a thick layer of collagen surrounding a circular collagen Detection Zone. After incubation, invading cells move into the detection zone, where they can be unambiguously quantified using a microscope or a plate-reader.
Features & Benefits
- Monitor cell invasion entirely in 3D
- Orisâ¢ platform enables you to distinguish different cell behavior in 2D cell migration and 3D cell invasion assay
- Physiologically Relevant: No artificial membranes or inserts required
- Versatile: Supports real-time monitoring or end-point analysis
Easy Analysis: Invasion can be quantified using image analysis or plate readers; no elaborate cell tracking software needed
Cell invasion assays are important tools for cancer research. Scientists studying cancer perform cell invasion assays to measure the cell movement through an extracellular matrix. By varying the conditions of the cell culture (e.g. adding new drugs), scientists can identify conditions that prevent or accelerate cell invasion. Through these studies, new treatments for cancer can be identified for potential therapeutic use.
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